International Journal of Advanced Technology and Engineering Exploration (IJATEE) ISSN (P): 2394-5443 ISSN (O): 2394-7454 Vol - 10, Issue - 105, August 2023
  1. 1
    Google Scholar
Deep learning-based computer assisted detection techniques for malaria parasite using blood smear images

Shankar Shambhu, Deepika Koundal and Prasenjit Das

Abstract

Malaria remains a significant global health concern, impacting various regions worldwide. Achieving effective treatment and reducing mortality rates hinges on early and accurate diagnosis. In the year 2021, the World Health Organization (WHO) reported a staggering 619,000 deaths attributed to malaria. Additionally, approximately 214 million individuals were afflicted by this disease during that period. Hence, this study introduces two distinct deep-learning algorithms tailored for malaria disease classification. The first method employs a binary classifier convolutional neural network (CNN) model, attaining an accuracy (ACC) of 90.20%. The second method introduces a customized CNN model that exhibits even greater ACC, reaching an impressive 96.02%. These advanced deep learning (DL) techniques hold the potential to enhance the precision (PRE) and efficiency of malaria diagnosis, ultimately facilitating early disease detection. The study provides comprehensive insights into the proposed models. Model 1 involves malaria disease classification employing a CNN-based binary classifier, while Model 2 adopts a customized CNN architecture. The methodology section elucidates the details of these models, their design, and the execution of experiments undertaken to evaluate their performance. Notably, the proposed method is juxtaposed with the state-of-the-art approach, demonstrating superior results in accurately discerning infected and uninfected malaria blood cell images.

Keyword

Malaria classification, Deep learning, Binary classifier, Customized CNN model, Image classification, Parasite detection.

Cite this article

Shambhu S, Koundal D, Das P

Refference

[1][1]https://www.who.int/news-room/fact-sheets/detail/malaria. Accessed 10 December 2022.

[2][2]https://www.malariasite.com/malaria-india/. Accessed 3 May 2023.

[3][3]Centers for disease control and prevention. Ross and the discovery that mosquitoes transmit malaria parasites. https://www.cdc.gov/malaria/about/history/ross.html. Accessed 3 May 2023.

[4][4]May Z, Aziz SS. Automated quantification and classification of malaria parasites in thin blood smears. In international conference on signal and image processing applications 2013 (pp. 369-73). IEEE.

[5][5]https://www.who.int/news-room/questions-and-answers/item/do-all-mosquitoes-transmit-malaria. Accessed 3 May 2023.

[6][6]Gilles HM. Management of severe and complicated malaria. A practical handbook. World Health Organization; 1991.

[7][7]Murphy SC, Breman JG. Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycemia, and complications of pregnancy. The Intolerable Burden of Malaria: A New Look at the Numbers: Supplement to Volume 64 (1) of the American Journal of Tropical Medicine and Hygiene. 2001.

[8][8]Sachs J, Malaney P. The economic and social burden of malaria. Nature. 2002; 415(6872):680-5.

[9][9]Chahar R, Dubey AK, Narang SK. A review and meta-analysis of machine intelligence approaches for mental health issues and depression detection. International Journal of Advanced Technology and Engineering Exploration. 2021; 8(83):1279-314.

[10][10]Rosado L, Correia DCJM, Elias D, S CJ. A review of automatic malaria parasites detection and segmentation in microscopic images. Anti-Infective Agents. 2016; 14(1):11-22.

[11][11]Tek FB, Dempster AG, Kale I. Computer vision for microscopy diagnosis of malaria. Malaria Journal. 2009; 8:1-4.

[12][12]Razin WR, Gunawan TS, Kartiwi M, Yusoff NM. Malaria parasite detection and classification using CNN and YOLOv5 architectures. In 8th international conference on smart instrumentation, measurement and applications 2022 (pp. 277-81). IEEE.

[13][13]Poostchi M, Silamut K, Maude RJ, Jaeger S, Thoma G. Image analysis and machine learning for detecting malaria. Translational Research. 2018; 194:36-55.

[14][14]Alharbi AH, Lin M, Ashwini B, Jabarulla MY, Shah MA. Detection of peripheral malarial parasites in blood smears using deep learning models. Computational Intelligence and Neuroscience. 2022; 2022:1-11.

[15][15]Marques G, Ferreras A, De LTI. An ensemble-based approach for automated medical diagnosis of malaria using EfficientNet. Multimedia Tools and Applications. 2022; 81(19):28061-78.

[16][16]Fuhad KM, Tuba JF, Sarker MR, Momen S, Mohammed N, Rahman T. Deep learning based automatic malaria parasite detection from blood smear and its smartphone based application. Diagnostics. 2020; 10(5):1-22.

[17][17]Simon A, Vinayakumar R, Sowmya V, Soman KP, Gopalakrishnan EA. A deep learning approach for patch-based disease diagnosis from microscopic images. In classification techniques for medical image analysis and computer aided diagnosis 2019 (pp. 109-27). Academic Press.

[18][18]Dubey A, Gupta U, Jain S. Medical data clustering and classification using TLBO and machine learning algorithms. Computers, Materials and Continua. 2021; 70(3):4523-43.

[19][19]Maqsood A, Farid MS, Khan MH, Grzegorzek M. Deep malaria parasite detection in thin blood smear microscopic images. Applied Sciences. 2021; 11(5):1-19.

[20][20]Rajaraman S, Silamut K, Hossain MA, Ersoy I, Maude RJ, Jaeger S, et al. Understanding the learned behavior of customized convolutional neural networks toward malaria parasite detection in thin blood smear images. Journal of Medical Imaging. 2018; 5(3):1-11.

[21][21]Raj M, Sharma R, Sain D. A deep convolutional neural network for detection of malaria parasite in thin blood smear images. In 10th international conference on communication systems and network technologies 2021 (pp. 510-4). IEEE.

[22][22]Minarno AE, Aripa L, Azhar Y, Munarko Y. Classification of malaria cell image using inception-V3 architecture. JOIV: International Journal on Informatics Visualization. 2023; 7(2):273-8.

[23][23]Siłka W, Wieczorek M, Siłka J, Woźniak M. Malaria detection using advanced deep learning architecture. Sensors. 2023; 23(3):1-21.

[24][24]Krishnadas P, Chadaga K, Sampathila N, Rao S, Prabhu S. Classification of malaria using object detection models. Informatics. 2022; 9(4):1-18.

[25][25]Sifat MM, Islam MM. A fully automated system to detect malaria parasites and their stages from the blood smear. In region 10 symposium 2020 (pp. 1351-4). IEEE.

[26][26]Sampathila N, Shet N, Basu A. Computational approach for diagnosis of malaria through classification of malaria parasite from microscopic image of blood smear. Biomedical Research. 2018; 29(18):3464-8.

[27][27]Li D, Ma Z. Residual attention learning network and SVM for malaria parasite detection. Multimedia Tools and Applications. 2022; 81(8):10935-60.

[28][28]Roy K, Sharmin S, Mukta RM, Sen A. Detection of malaria parasite in Giemsa blood sample using image processing. International Journal of Computer Science and Information Technology. 2018; 10(1):55-65.

[29][29]Nayak S, Kumar S, Jangid M. Malaria detection using multiple deep learning approaches. In 2019 2nd international conference on intelligent communication and computational techniques 2019 (pp. 292-7). IEEE.

[30][30]Maduri PK, Agrawal S, Rai A, Chaubey S. Malaria detection using image processing and machine learning. In 3rd international conference on advances in computing, communication control and networking 2021 (pp. 1789-92). IEEE.

[31][31]Francies ML, Ata MM, Mohamed MA. A robust multiclass 3D object recognition based on modern YOLO deep learning algorithms. Concurrency and Computation: Practice and Experience. 2022; 34(1):e6517.

[32][32]Setyawan D, Wardoyo R, Wibowo ME, Murhandarwati EE, Jamilah J. Malaria classification using convolutional neural network: a review. In sixth international conference on informatics and computing 2021 (pp. 1-9). IEEE.

[33][33]Hung J, Carpenter A. Applying faster R-CNN for object detection on malaria images. In proceedings of the IEEE conference on computer vision and pattern recognition workshops 2017 (pp. 56-61).

[34][34]Var E, Tek FB. Malaria parasite detection with deep transfer learning. In 3rd international conference on computer science and engineering 2018 (pp. 298-302). IEEE.

[35][35]Yang F, Poostchi M, Yu H, Zhou Z, Silamut K, Yu J, et al. Deep learning for smartphone-based malaria parasite detection in thick blood smears. IEEE Journal of Biomedical and Health Informatics. 2019; 24(5):1427-38.

[36][36]Iradukunda O, Che H, Uwineza J, Bayingana JY, Bin-imam MS, Niyonzima I. Malaria disease prediction based on machine learning. In international conference on signal, information and data processing 2019 (pp. 1-7). IEEE.

[37][37]Prakash SS, Kovoor BC, Visakha K. Convolutional neural network based malaria parasite infection detection using thin microscopic blood smear samples. In second international conference on inventive research in computing applications 2020 (pp. 308-13). IEEE.

[38][38]Shekar G, Revathy S, Goud EK. Malaria detection using deep learning. In 4th international conference on trends in electronics and informatics (48184) 2020 (pp. 746-50). IEEE.

[39][39]Umer M, Sadiq S, Ahmad M, Ullah S, Choi GS, Mehmood A. A novel stacked CNN for malarial parasite detection in thin blood smear images. IEEE Access. 2020; 8:93782-92.

[40][40]Joshi AM, Das AK, Dhal S. Deep learning based approach for malaria detection in blood cell images. In region 10 conference 2020 (pp. 241-6). IEEE.

[41][41]Paul A, Bania RK. Malaria parasite classification using deep convolutional neural network. In international conference on computational intelligence and computing applications 2021 (pp. 1-6). IEEE.

[42][42]Aimi SAN, Yusoff M, Zeehaida M. Colour image segmentation approach for detection of malaria parasites using various colour models and k-means clustering. WSEAS Transactions on Biology and Biomedicine. 2013; 10(1):41-55.

[43][43]Savkare SS, Narote SP. Automatic detection of malaria parasites for estimating parasitemia. International Journal of Computer Science and Security. 2011; 5(3):310-5.

[44][44]https://lhncbc.nlm.nih.gov/LHC-downloads/dataset.html. Accessed 04 May 2020.

[45][45]Patel M, Shah M. Transfer learning with fine-tuned deep CNN model for COVID-19 diagnosis from chest X-ray images. International Journal of Advanced Technology and Engineering Exploration. 2023; 10(103):720-40.

[46][46]Jameela T, Athota K, Singh N, Gunjan VK, Kahali S. Deep learning and transfer learning for malaria detection. Computational Intelligence and Neuroscience. 2022; 2022:1-14.

[47][47]Shah D, Kawale K, Shah M, Randive S, Mapari R. Malaria parasite detection using deep learning:(beneficial to humankind). In 4th international conference on intelligent computing and control systems 2020 (pp. 984-8). IEEE.

[48][48]Fatima T, Farid MS. Automatic detection of Plasmodium parasites from microscopic blood images. Journal of Parasitic Diseases. 2020; 44(1):69-78.

[49][49]Sharma A, Vaishampayan C, Santlani K, Sunhare M, Arya M, Gupta S. Malaria parasite detection using deep learning. International Journal for Research in Applied Science & Engineering Technology. 2020; 8(V):163-8.

[50][50]Vijayalakshmi A. Deep learning approach to detect malaria from microscopic images. Multimedia Tools and Applications. 2020; 79:15297-317.

[51][51]Rajaraman S, Antani SK, Poostchi M, Silamut K, Hossain MA, Maude RJ, et al. Pre-trained convolutional neural networks as feature extractors toward improved malaria parasite detection in thin blood smear images. Peer J. 2018; 6:e4568.